Recombinant Human Anti-IAV HA Antibody (5J8) (CAT#: PABL-207)
Recombinant Human Antibody (5J8) is capable of binding to IAV HA, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-IAV HA mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-IAV HA mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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FuncS
Figure 1 Therapeutic efficacy of MAb 5J8 against disease caused bythe 1918 influenza A(H1N1) virus in mice.
Mice were inoculated onday 0 and treated on day 1 with the indicated antibody and dose. In each group, six mice were monitored every other day for survival.
Krause, J. C., Tsibane, T., Tumpey, T. M., Huffman, C. J., Basler, C. F., & Crowe, J. E. (2011). A broadly neutralizing human monoclonal antibody that recognizes a conserved, novel epitope on the globular head of the influenza H1N1 virus hemagglutinin. Journal of virology, 85(20), 10905-10908.
Specifications
- Immunogen
- Influenza a virus Hemagglutinin
- Host Species
- Human
- Derivation
- Human
- Type
- IgG
- Specificity
- Tested positive against native IAV HA
- Species Reactivity
- IAV
- Clone
- 5J8
- Applications
- FuncS
Product Property
- Purity
- >95% by SDS-PAGE and HPLC analysis
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Applications
- Application Notes
- This antibody has been reported for use in Function Assay.
Target
- Alternative Names
- HA; hemagglutinin; haemagglutinin
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Single Domain Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-223 | Recombinant Human Anti-IAV HA1 chain Antibody (C05) | WB, ELISA, FuncS | IgG |
| PABC-160 | Human Anti-HA Recombinant Antibody (PABC-160) | Neut, ELISA, FC | Human IgG |
| PABC-233 | Recombinant Human Anti-H3N2 HA Antibody (F045-092) | Neut | IgG |
| HPAB-0373-YJ | Mouse Anti-HA Recombinant Antibody (HPAB-0373-YJ) | ELISA, Neut, IF, FuncS | Mouse IgG2a |
| HPAB-S0058-YC | Mouse Anti-HA Recombinant Antibody (clone HC19) | Neut | Mouse IgG1, λ |
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Cite This Product
To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# PABL-207, RRID: AB_3111637)
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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